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Fragment Library

Our Comprehensive Collection contains libraries of lead-like compounds selected according to the following criteria: 

  • MW less than 300;
  • clogP less than 3.

There are over 32 000 compounds meeting the above characteristics and 22 000 of them are available ex-stock. To make even more narrow selections of lead-like fragments we have applied additional filtering, including: 

  • Rotatable bond count less than 5;
  • HBA less than 3 and HBD less than 2; 
  • Topological polar surface area less than 70 A.

Of these compounds we have 9 000 in stock and 2 900 can be readily synthesized. 

 

Needless to say that these most attractive libraries are of special interest to those of our customers, who are in fragment based drug discovery.

Immediately downloaded here can be the 32 000 compound library. More narrow selections will be sent promptly upon request.

 

 
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